/* Celtic Biotech – Option D Bootstrap theme (local-only, Cloudflare-ready) */
:root {
  --cb-primary: #046bd2;
  --cb-primary-dark: #045cb4;
  --cb-green-dark: #46673e;
  --cb-green-pale: #6b8c63;
  --cb-heading: #46673e;
  --cb-text: #333333;
  --cb-bg: #F0F5FA;
  --cb-white: #ffffff;
  --cb-border: #D1D5DB;
  /* Consistent rounded corners and 3D drop shadow for panels, cards, images, tables */
  --cb-radius: 0.5rem;
  --cb-shadow: 0 4px 6px rgba(0, 0, 0, 0.07), 0 2px 4px rgba(0, 0, 0, 0.05);
}
body { font-family: 'Roboto', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif; color: var(--cb-text); }
/* Skip link: off-screen until focused */
.skip-link {
  position: absolute;
  top: -3rem;
  left: 0.5rem;
  z-index: 9999;
  padding: 0.5rem 1rem;
  background: var(--cb-primary);
  color: #fff;
  font-weight: 600;
  text-decoration: none;
  border-radius: 0.25rem;
  transition: top 0.2s;
}
.skip-link:focus {
  top: 0.5rem;
  outline: 2px solid var(--cb-green-dark);
  outline-offset: 2px;
}
/* Headings: slightly lighter weight for a softer, more appealing look */
h1, h2, h3, h4, h5, h6,
.h1, .h2, .h3, .h4, .h5, .h6,
main h1, main h2, main h3, main h4, main h5, main h6 {
  font-family: 'Roboto', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif !important;
  color: var(--cb-heading);
  font-weight: 500;
}
a { color: var(--cb-green-dark); }
a:hover { color: var(--cb-green-pale); }
.btn-primary { background-color: var(--cb-green-dark); border-color: var(--cb-green-dark); }
.btn-primary:hover { background-color: var(--cb-green-pale); border-color: var(--cb-green-pale); }
/* Navbar: sticky, pale green (footer match) 33% strength left → 100% right */
nav.navbar,
.navbar.navbar-expand-lg {
  position: sticky;
  top: 0;
  z-index: 1030;
  background: linear-gradient(to right, #fbfcfb 0%, #f2f6f1 100%) !important;
  border-bottom: 1px solid var(--cb-border);
}
.navbar .navbar-nav .nav-link {
  color: var(--cb-green-pale);
  border-radius: 0.25rem;
  transition: background-color 0.2s, color 0.2s;
}
.navbar .navbar-nav .nav-link:hover {
  color: var(--cb-green-dark);
  background-color: rgba(107, 140, 99, 0.15);
}
.navbar .navbar-nav .nav-link.active {
  color: var(--cb-green-dark);
  font-weight: 600;
  background-color: rgba(70, 103, 62, 0.12);
}
.navbar .navbar-toggler { border-color: var(--cb-border); }
.navbar .navbar-toggler-icon { filter: none; }
/* Narrow viewport: hamburger (left), logo (centred), gear (right); consistent height; hamburger always visible */
@media (max-width: 991.98px) {
  .navbar .container {
    position: relative;
    display: flex;
    flex-wrap: wrap;
    align-items: center;
    justify-content: space-between;
    padding-top: 0.5rem;
    padding-bottom: 0.5rem;
    min-height: 3.25rem;
  }
  .navbar .container .navbar-toggler {
    order: 1;
    flex-shrink: 0;
    align-self: center;
    width: 2.25rem;
    height: 2.25rem;
    padding: 0.25rem;
    border: 1px solid var(--cb-border);
    border-radius: var(--cb-radius);
    background: var(--cb-white);
    display: inline-flex;
    align-items: center;
    justify-content: center;
  }
  .navbar .container .navbar-brand.cb-navbar-brand {
    position: absolute;
    left: 50%;
    top: 1.625rem; /* half of min-height 3.25rem – keep logo in first row when menu is open */
    transform: translate(-50%, -50%);
    order: 2;
    min-height: 0;
    align-self: center;
    z-index: 1;
  }
  .navbar .container .navbar-brand.cb-navbar-brand .cb-brand-symbol {
    height: 2.25rem;
    max-height: 2.25rem;
  }
  .navbar .container .navbar-brand.cb-navbar-brand .cb-brand-text {
    font-size: 1.2rem;
  }
  .navbar .container .cb-settings-wrap {
    order: 3;
    flex-shrink: 0;
    margin-left: auto;
    align-self: center;
  }
  .navbar .container .cb-settings-wrap .cb-settings-btn {
    width: 2.25rem;
    height: 2.25rem;
    padding: 0;
    border: 1px solid var(--cb-border);
    border-radius: var(--cb-radius);
    background: var(--cb-white);
  }
  .navbar .container .navbar-collapse {
    order: 4;
    flex-basis: 100%;
    width: 100%;
    margin-left: 2.5rem; /* clear hamburger so first nav link doesn’t overlap */
    margin-top: 0.5rem;
  }
  .navbar-collapse {
    display: flex;
    flex-direction: row;
    flex-wrap: wrap;
    align-items: center;
    gap: 0.4rem 0.75rem;
  }
  .navbar-collapse .navbar-nav {
    display: flex;
    flex-direction: row;
    flex-wrap: wrap;
    margin-bottom: 0;
    gap: 0.4rem 0.65rem;
  }
  .navbar-collapse .navbar-nav .nav-item {
    margin: 0;
  }
  .navbar-collapse .nav-link {
    padding: 0.45rem 0.7rem;
    border-radius: 0.25rem;
  }
  .navbar-collapse .nav-link.active {
    background-color: rgba(70, 103, 62, 0.2);
    text-decoration: underline;
    text-underline-offset: 0.2em;
  }
  .navbar-collapse .nav-link:hover {
    background-color: rgba(107, 140, 99, 0.25);
  }
  .navbar,
  .navbar .container,
  .navbar .cb-settings-wrap {
    overflow: visible;
  }
}
/* Navbar brand: text + symbol – vertically centered, scaled */
.cb-navbar-brand {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 0.2rem;
  text-decoration: none;
  color: inherit;
  min-height: 4.56rem;
}
.cb-brand-text {
  font-family: 'Roboto', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif;
  font-weight: 500;
  letter-spacing: 0.02em;
  color: var(--cb-heading);
  font-size: 1.52rem;
  line-height: 1;
  white-space: nowrap;
  display: inline-flex;
  align-items: center;
  align-self: center;
  text-transform: uppercase !important;
}
.cb-brand-symbol {
  display: block;
  height: 4.56rem;
  width: auto;
  max-height: 4.56rem;
  object-fit: contain;
  flex-shrink: 0;
  align-self: center;
  vertical-align: middle;
}
.navbar .navbar-brand img:not(.cb-brand-symbol) { max-height: 96px !important; width: auto !important; }
/* Footer nav: same green scheme */
footer .nav-link {
  color: var(--cb-green-pale);
  border-radius: 0.25rem;
  transition: background-color 0.2s, color 0.2s;
}
footer .nav-link:hover {
  color: var(--cb-green-dark);
  background-color: rgba(70, 103, 62, 0.12);
}
/* Footer: very pale green tint */
footer { background-color: #f2f6f1; border-top: 1px solid #e6e6e6; }
/* Copyright and footer text in dark green */
footer p, footer .text-muted, footer .small { color: var(--cb-green-dark) !important; }
/* Shared accordion panels: FAQ + Clinical trials extracts – same look (green palette, radius, shadow) */
.cb-accordion .accordion-item {
  border: 1px solid rgba(70,103,62,0.25);
  border-radius: var(--cb-radius);
  overflow: hidden;
  margin-bottom: 0.5rem;
  background-color: #fff;
  box-shadow: var(--cb-shadow);
  scroll-margin-top: 6rem;
}
.cb-accordion .accordion-item:first-of-type { border-top-left-radius: var(--cb-radius); border-top-right-radius: var(--cb-radius); }
.cb-accordion .accordion-item:last-of-type { border-bottom-left-radius: var(--cb-radius); border-bottom-right-radius: var(--cb-radius); }
.cb-accordion .accordion-button { background-color: #fff !important; color: var(--cb-green-dark) !important; border: none; border-bottom: 1px solid rgba(70,103,62,0.15); padding: 1rem 1.25rem; font-weight: 600; }
.cb-accordion .accordion-button.collapsed { color: var(--cb-green-dark) !important; }
.cb-accordion .accordion-button:not(.collapsed) { background-color: #f8faf8 !important; color: var(--cb-green-pale) !important; box-shadow: none; border-bottom-color: rgba(70,103,62,0.2); }
.cb-accordion .accordion-button:hover { background-color: #f8faf8 !important; color: var(--cb-green-dark); }
.cb-accordion .accordion-button:focus { box-shadow: 0 0 0 0.2rem rgba(107,140,99,0.35) !important; border-color: transparent; outline: none; }
.cb-accordion .accordion-body { background-color: #fff; color: var(--cb-text); padding: 1.25rem; border-top: 1px solid rgba(70,103,62,0.1); line-height: 1.6; }
.cb-accordion .accordion-button::after { filter: brightness(0) saturate(100%); opacity: 0.7; }
/* Toolbar above accordion (FAQ / Clinical trials): lead + Expand all / Collapse all on one line */
.cb-accordion-toolbar {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  justify-content: space-between;
  gap: 0.5rem;
  margin-bottom: 1rem;
}
.cb-accordion-toolbar .cb-accordion-toolbar-buttons { display: flex; gap: 0.5rem; }
/* First page heading (e.g. FAQ, CB-24, Media) centred on all pages */
main h1:first-of-type { text-align: center; }
/* Headings with "— … —" style: centre them */
.cb-heading-dash { text-align: center; }
/* Nav logo ~2x larger to match original */
/* Body and panel text: consistent dark gray (headings/bold stay green via main h1 etc.) */
.cb-text-light-green, .media-page .card .card-text, main.clinical-trials-content p, main.clinical-trials-content li { color: var(--cb-text); }
.cb-divider-text { text-align: center; font-weight: 600; color: var(--cb-heading); margin: 1.5rem 0; letter-spacing: 0.05em; }
/* Divider with text and lines (e.g. EXTRACTS FROM PUBLICATIONS) */
.cb-divider-with-text {
  display: flex;
  align-items: center;
  gap: 0.75rem;
  margin: 1.5rem 0;
}
.cb-divider-with-text .cb-divider-line {
  flex: 1;
  height: 1px;
  background: var(--cb-border);
}
.cb-divider-with-text .cb-divider-label {
  font-weight: 500;
  color: var(--cb-heading);
  letter-spacing: 0.05em;
  font-size: 1.5rem;
  white-space: nowrap;
}
/* Clinical trials: references table of links (narrower, centred) */
.cb-trials-refs-table-wrap { overflow-x: auto; max-width: 720px; margin-left: auto; margin-right: auto; }
.cb-trials-refs-table {
  width: 100%;
  border-collapse: collapse;
  border: 1px solid rgba(70, 103, 62, 0.2);
  border-radius: var(--cb-radius);
  overflow: hidden;
  background: #fff;
  box-shadow: var(--cb-shadow);
}
.cb-trials-refs-table thead {
  background-color: #f2f6f1;
  border-bottom: 2px solid rgba(70, 103, 62, 0.25);
}
.cb-trials-refs-table th {
  padding: 0.75rem 1rem;
  text-align: left;
  font-weight: 600;
  color: var(--cb-heading);
  font-size: 0.9rem;
}
.cb-trials-refs-table td {
  padding: 0.65rem 1rem;
  border-bottom: 1px solid rgba(70, 103, 62, 0.1);
  color: var(--cb-text);
  vertical-align: middle;
}
.cb-trials-refs-table tbody tr:last-child td { border-bottom: none; }
.cb-trials-refs-table tbody tr:hover { background-color: #f8faf8; }
.cb-trials-refs-table td a {
  color: var(--cb-green-dark);
  font-weight: 500;
  text-decoration: none;
}
.cb-trials-refs-table td a:hover { color: var(--cb-green-pale); text-decoration: underline; }
/* Divider with star (like old site) */
.cb-divider-star {
  display: flex;
  align-items: center;
  gap: 0.75rem;
  margin: 1rem 0;
}
.cb-divider-star .cb-divider-line {
  flex: 1;
  height: 1px;
  background: var(--cb-border);
}
.cb-divider-star .cb-star {
  flex-shrink: 0;
  color: var(--cb-green-dark);
  line-height: 1;
}
.cb-divider-star .cb-star svg {
  width: 1rem;
  height: 1rem;
  display: block;
}
/* Endorsed By: one block with heading close to marquee, white background */
.cb-endorsed-section {
  margin-top: -1rem;
  padding: 1.25rem 0 2rem;
  background: #fff;
  border-top: 1px solid rgba(70, 103, 62, 0.08);
}
.cb-endorsed-section .cb-endorsed-heading {
  margin-bottom: 1rem;
  font-size: 1.25rem;
  letter-spacing: 0.02em;
  color: var(--cb-green-dark);
}
.cb-endorsed-section .cb-logo-marquee { margin-top: 0; }
.cb-marquee-wrap { overflow: hidden; }
.cb-logo-marquee { overflow: hidden; padding: 1.5rem 0; }
.cb-logo-track { display: flex; flex-wrap: nowrap; gap: 2rem; animation: cb-marquee 25s linear infinite; width: max-content; }
.cb-logo-track img { max-height: 120px; width: auto; object-fit: contain; display: block; flex-shrink: 0; }
@keyframes cb-marquee { 0% { transform: translateX(0); } 100% { transform: translateX(-33.333%); } }
/* Centre videos and large images */
.ratio.ratio-16x9, .ratio.ratio-4x3, main video.img-fluid, main .img-fluid.mb-4 { margin-left: auto; margin-right: auto; display: block; }
/* Standalone content images: consistent rounded corners and 3D shadow */
main img.img-fluid {
  border-radius: var(--cb-radius);
  box-shadow: var(--cb-shadow);
  max-width: 100%;
  height: auto;
}
/* Any card in main (fallback for cards without .media-card / .team-card) */
main .card {
  border-radius: var(--cb-radius);
  overflow: hidden;
  box-shadow: var(--cb-shadow);
}
/* Bootstrap tables in main */
main .table {
  border-radius: var(--cb-radius);
  overflow: hidden;
  box-shadow: var(--cb-shadow);
}
main .table thead th { border-top-left-radius: var(--cb-radius); border-top-right-radius: var(--cb-radius); }
/* List groups and blockquotes as rectangular elements */
main .list-group, main blockquote {
  border-radius: var(--cb-radius);
  box-shadow: var(--cb-shadow);
  overflow: hidden;
}
/* Media page: card styling and image area with padding so images don't touch borders */
.media-page .media-card {
  border: 1px solid rgba(70, 103, 62, 0.15);
  border-radius: var(--cb-radius);
  overflow: hidden;
  box-shadow: var(--cb-shadow);
  transition: box-shadow 0.2s ease, border-color 0.2s ease;
}
.media-page .media-card:hover {
  box-shadow: 0 6px 14px rgba(0, 0, 0, 0.08), 0 3px 6px rgba(70, 103, 62, 0.08);
  border-color: rgba(70, 103, 62, 0.25);
}
.media-page .card .card-img-wrap {
  padding: 1.25rem;
  background: #f8f9f8;
  min-height: 120px;
  display: flex;
  align-items: center;
  justify-content: center;
  border-radius: var(--cb-radius) var(--cb-radius) 0 0;
}
.media-page .card .card-img-wrap img {
  width: auto;
  max-width: 100%;
  height: auto;
  max-height: 140px;
  object-fit: contain;
  display: block;
  border-radius: var(--cb-radius);
}
.media-page .card .card-body {
  padding: 1.25rem 1.25rem 1.25rem;
}
/* Media page: collapsible card header (date + title + toggle) */
.media-page .media-card-header {
  display: flex;
  align-items: flex-start;
  gap: 0.5rem;
  padding: 1rem 1.25rem;
  cursor: pointer;
  background: var(--cb-white);
  border-bottom: 1px solid rgba(70, 103, 62, 0.1);
  transition: background-color 0.2s;
}
.media-page .media-card-header:hover {
  background-color: #f8faf8;
}
.media-page .media-card-header .media-card-toggle {
  flex-shrink: 0;
  font-size: 1.1rem;
  transition: transform 0.2s ease;
}
.media-page .media-card-header.media-card-expanded .media-card-toggle {
  transform: rotate(180deg);
  line-height: 1.2;
  color: var(--cb-green-dark);
  width: 1.25em;
  text-align: center;
}
.media-page .media-card-header .media-card-header-top {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.5rem;
  width: 100%;
}
.media-page .media-card-header .media-card-header-text {
  flex: 1;
  min-width: 0;
}
.media-page .media-card-header .card-title { color: var(--cb-heading); }
.media-page .media-card-header .card-text { color: var(--cb-text); }
.media-page .media-card .collapse .card-body { border-top: none; }
/* When expanded, hide the collapsed-state trigger so only collapse content (image, header, body) shows */
.media-page .media-card:has(.collapse.show) .media-card-trigger { display: none !important; }
/* Pipeline page: 4 panels with pale green tint, dotted border, dividers, phase button */
.cb-pipeline-panel {
  background-color: #f2f6f1;
  border: 2px dotted rgba(70, 103, 62, 0.35);
  border-radius: var(--cb-radius);
  padding: 1.25rem 1.25rem 1.5rem;
  height: 100%;
  display: flex;
  flex-direction: column;
  text-align: center;
  box-shadow: var(--cb-shadow);
}
.cb-pipeline-panel-title {
  font-size: 2rem;
  font-weight: 600;
  color: var(--cb-heading);
  margin-bottom: 0.25rem;
}
.cb-pipeline-panel-subtitle {
  font-size: 1.2rem;
  font-weight: 500;
  color: var(--cb-heading);
  text-transform: uppercase;
  letter-spacing: 0.03em;
  margin-bottom: 0.75rem;
}
.cb-pipeline-panel-divider {
  border: none;
  border-top: 1px solid var(--cb-border);
  margin: 0 0 1rem;
}
.cb-pipeline-panel-list {
  list-style: disc;
  padding-left: 1.5rem;
  margin-bottom: 1.25rem;
  flex: 1;
  color: var(--cb-text);
  font-size: 1.07rem;
  line-height: 1.5;
  text-align: left;
  border-radius: var(--cb-radius);
}
.cb-pipeline-panel-list li { margin-bottom: 0.5rem; }
.cb-pipeline-phase {
  display: inline-block;
  background-color: var(--cb-green-dark);
  color: #fff;
  font-size: 1.125rem;
  font-weight: 600;
  text-transform: uppercase;
  letter-spacing: 0.04em;
  padding: 0.5rem 0.85rem;
  border-radius: 0.35rem;
}
/* Our team: pale green card background, image with gap so it doesn't touch border */
.team-card {
  background-color: #f2f6f1;
  border: 1px solid rgba(70, 103, 62, 0.12);
  border-radius: var(--cb-radius);
  overflow: hidden;
  padding: 1.25rem 1.25rem 0;
  box-shadow: var(--cb-shadow);
}
.team-card .card-img-wrap {
  width: 100%;
  aspect-ratio: 1;
  overflow: hidden;
  border-radius: 50%;
  border: 1px solid var(--cb-green-dark);
  background: #f9f9f9;
  margin: 0 auto 1rem;
  max-width: 100%;
  box-sizing: border-box;
  box-shadow: var(--cb-shadow);
}
.team-card .card-img-wrap img { width: 100%; height: 100%; object-fit: cover; display: block; }
.team-card .card-body { padding: 0 0 1.25rem; background-color: transparent; }
/* Team biography collapse: role line with chevron on right; chevron rotates when expanded */
.team-bio-trigger-row {
  color: var(--cb-green-dark);
  text-decoration: none;
  min-height: 1.5rem;
}
.team-bio-trigger-row:hover { color: var(--cb-green-pale); }
.team-bio-trigger-row .team-role { flex: 1; min-width: 0; text-align: left; }
.team-bio-trigger-row .team-bio-toggle {
  flex-shrink: 0;
  font-size: 1rem;
  transition: transform 0.28s ease;
}
.team-bio-trigger-row[aria-expanded="true"] .team-bio-toggle { transform: rotate(180deg); }
.team-card .team-bio-collapse .card-text { margin-top: 0.5rem; margin-bottom: 0; }

/* Contact form: card, header, fields, submit, footer */
.cb-contact-form-wrap { max-width: 640px; }
.cb-contact-alerts { margin-bottom: 1rem; }
.cb-contact-form-card {
  background: #fff;
  border-radius: var(--cb-radius);
  box-shadow: var(--cb-shadow);
  overflow: hidden;
  border: 1px solid rgba(70, 103, 62, 0.15);
}
.cb-contact-form-header {
  background-color: var(--cb-green-dark);
  color: #fff;
  padding: 1rem 1.25rem;
  margin: 0;
}
.cb-contact-form-title {
  margin: 0;
  font-size: 1.25rem;
  font-weight: 600;
  color: #fff;
}
.cb-contact-form-intro,
.cb-contact-form-required {
  padding: 0 1.25rem;
  margin: 0.75rem 0 0;
  font-size: 0.9rem;
  color: var(--cb-text);
}
.cb-contact-form-required { margin-top: 0.25rem; margin-bottom: 0; }
.cb-contact-form {
  padding: 1rem 1.25rem 1.25rem;
}
.cb-contact-form .form-label {
  font-weight: 600;
  color: var(--cb-heading);
  margin-bottom: 0.35rem;
}
.cb-contact-form .form-control {
  border-radius: var(--cb-radius);
  border: 1px solid var(--cb-border);
}
.cb-contact-form .form-control:focus {
  border-color: var(--cb-green-pale);
  box-shadow: 0 0 0 0.2rem rgba(107, 140, 99, 0.25);
}
.cb-contact-submit {
  background-color: var(--cb-green-dark) !important;
  border-color: var(--cb-green-dark) !important;
  color: #fff !important;
  font-weight: 600;
  padding: 0.6rem 1.5rem;
  border-radius: var(--cb-radius);
  width: 100%;
  max-width: 200px;
}
.cb-contact-submit:hover {
  background-color: var(--cb-green-pale) !important;
  border-color: var(--cb-green-pale) !important;
  color: #fff !important;
}
.cb-contact-form-footer {
  padding: 0 1.25rem 1rem;
  margin: 0;
  font-size: 0.8rem;
  color: var(--cb-text);
}
.cb-contact-form-footer a { color: var(--cb-primary); }
.cb-contact-form-footer a:hover { text-decoration: underline; }

/* Settings gear and panel */
.cb-settings-wrap {
  position: relative;
  display: flex;
  align-items: center;
  margin-left: 0.5rem;
}
@media (min-width: 992px) {
  .navbar .container .navbar-collapse { order: 2; }
  .navbar .container .cb-settings-wrap { order: 3; }
}
.cb-settings-btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  width: 2.5rem;
  height: 2.5rem;
  padding: 0;
  border: 1px solid var(--cb-border);
  border-radius: var(--cb-radius);
  background: var(--cb-white);
  color: var(--cb-green-dark);
  cursor: pointer;
  transition: background-color 0.2s, color 0.2s, border-color 0.2s;
}
.cb-settings-btn:hover {
  background-color: #f8faf8;
  color: var(--cb-green-pale);
  border-color: var(--cb-green-pale);
}
.cb-settings-icon { flex-shrink: 0; font-size: 1.25rem; color: inherit; display: inline-block; }
.cb-settings-panel {
  position: absolute;
  top: 100%;
  right: 0;
  margin-top: 0.25rem;
  min-width: 14rem;
  padding: 0.75rem 0;
  background: var(--cb-white);
  border: 1px solid var(--cb-border);
  border-radius: var(--cb-radius);
  box-shadow: 0 6px 20px rgba(0, 0, 0, 0.15);
  z-index: 1060;
  overflow: hidden;
  display: block;
}
.cb-settings-label {
  display: block;
  padding: 0.5rem 1.25rem 0.35rem;
  font-size: 0.8rem;
  font-weight: 600;
  text-transform: uppercase;
  letter-spacing: 0.05em;
  color: var(--cb-green-dark);
}
.cb-settings-option {
  display: block;
  width: 100%;
  padding: 0.6rem 1.25rem 0.6rem 2.5rem;
  border: none;
  background: transparent;
  font-size: 1rem;
  color: var(--cb-text);
  text-align: left;
  cursor: pointer;
  transition: background-color 0.15s, color 0.15s;
  position: relative;
}
.cb-settings-option:hover {
  background-color: #f2f6f1;
  color: var(--cb-green-dark);
}
.cb-settings-option-active {
  font-weight: 700;
  color: var(--cb-green-dark) !important;
  background-color: rgba(70, 103, 62, 0.12);
}
.cb-settings-option-active::before {
  content: '';
  position: absolute;
  left: 1rem;
  top: 50%;
  transform: translateY(-50%);
  width: 0.5rem;
  height: 0.5rem;
  border-radius: 50%;
  background-color: currentColor;
}

/* Dark mode */
[data-theme="dark"] {
  --cb-primary: #7ab8a8;
  --cb-primary-dark: #5a9a8a;
  --cb-green-dark: #8fbc87;
  --cb-green-pale: #9bc492;
  --cb-heading: #c5ddc0;
  --cb-text: #e8ebe7;
  --cb-bg: #1a1f19;
  --cb-white: #252f23;
  --cb-border: #3d4d38;
  --cb-shadow: 0 4px 12px rgba(0, 0, 0, 0.35);
}
[data-theme="dark"] body { background-color: #1e261c; }
[data-theme="dark"] nav.navbar,
[data-theme="dark"] .navbar.navbar-expand-lg {
  background: linear-gradient(to right, #2d3d2a 0%, #252f23 100%) !important;
  border-bottom-color: #3d4d38;
}
[data-theme="dark"] .navbar .navbar-nav .nav-link:hover {
  background-color: rgba(155, 196, 146, 0.25);
  color: #c5ddc0;
}
[data-theme="dark"] .navbar .navbar-nav .nav-link.active {
  color: #c5ddc0 !important;
  background-color: rgba(155, 196, 146, 0.2);
}
@media (max-width: 991.98px) {
  [data-theme="dark"] .navbar-collapse .nav-link {
    color: #9bc492;
  }
  [data-theme="dark"] .navbar-collapse .nav-link:hover {
    background-color: rgba(155, 196, 146, 0.3);
    color: #c5ddc0;
  }
  [data-theme="dark"] .navbar-collapse .nav-link.active {
    color: #c5ddc0 !important;
    background-color: rgba(155, 196, 146, 0.25);
  }
}
[data-theme="dark"] .navbar .navbar-toggler {
  background-color: #2d3d2a;
  border-color: #9bc492;
  color: #9bc492;
}
[data-theme="dark"] .navbar .navbar-toggler-icon {
  filter: invert(1);
  opacity: 0.9;
}
[data-theme="dark"] .navbar .navbar-toggler:hover {
  background-color: #3d4d38;
  border-color: #c5ddc0;
  color: #c5ddc0;
}
[data-theme="dark"] footer { background-color: #2d3d2a; border-top-color: #3d4d38; }
[data-theme="dark"] footer .nav-link { color: #9bc492; }
[data-theme="dark"] footer .nav-link:hover {
  background-color: rgba(155, 196, 146, 0.25);
  color: #c5ddc0;
}
[data-theme="dark"] .cb-settings-btn { background: #252f23; border-color: #3d4d38; color: #9bc492; }
[data-theme="dark"] .cb-settings-btn:hover { background: #2d3d2a; color: #c5ddc0; }
[data-theme="dark"] .cb-settings-panel { background: #252f23; border-color: #3d4d38; }
[data-theme="dark"] .cb-settings-label { color: #9bc492; }
[data-theme="dark"] .cb-settings-option { color: #e8ebe7; }
[data-theme="dark"] .cb-settings-option:hover { background: #2d3d2a; color: #c5ddc0; }
[data-theme="dark"] .media-page .media-card,
[data-theme="dark"] .media-page .card { background: #252f23; border-color: #3d4d38; }
[data-theme="dark"] .media-page .media-card-header { background: #252f23; }
[data-theme="dark"] .media-page .media-card-header:hover { background-color: #2d3d2a; }
[data-theme="dark"] .media-page .media-card-header .media-card-toggle { color: var(--cb-green-pale); }
[data-theme="dark"] .media-page .media-card-header.media-card-expanded .media-card-toggle { color: var(--cb-green-dark); }
[data-theme="dark"] .media-page .card .card-img-wrap { background: #2d3d2a; }
[data-theme="dark"] .media-page .card .card-body,
[data-theme="dark"] .media-page .card .card-text,
[data-theme="dark"] .media-page .card .card-text.small { color: var(--cb-text); }
[data-theme="dark"] .text-muted { color: #9bc492 !important; }
/* Index: marquee / endorsed section */
[data-theme="dark"] .cb-endorsed-section {
  background: #252f23;
  border-top-color: #3d4d38;
}
[data-theme="dark"] .cb-endorsed-section .cb-endorsed-heading { color: var(--cb-heading); }
[data-theme="dark"] .cb-logo-marquee,
[data-theme="dark"] .cb-marquee-wrap { background: transparent; }
[data-theme="dark"] .cb-logo-track img { opacity: 0.9; }
/* Pipeline: 4 panels */
[data-theme="dark"] .cb-pipeline-panel {
  background-color: #252f23;
  border-color: #3d4d38;
}
[data-theme="dark"] .cb-pipeline-panel-title,
[data-theme="dark"] .cb-pipeline-panel-subtitle { color: var(--cb-heading); }
[data-theme="dark"] .cb-pipeline-panel-divider { border-top-color: #3d4d38; }
[data-theme="dark"] .cb-pipeline-panel-list { color: var(--cb-text); }
[data-theme="dark"] .cb-pipeline-phase { background-color: var(--cb-green-pale); color: #1a1f19; }
/* Clinical trials: reference table */
[data-theme="dark"] .cb-trials-refs-table-wrap { color: var(--cb-text); }
[data-theme="dark"] .cb-trials-refs-table {
  background: #252f23;
  border-color: #3d4d38;
  color: var(--cb-text);
}
[data-theme="dark"] .cb-trials-refs-table thead { background: #2d3d2a; border-color: #3d4d38; }
[data-theme="dark"] .cb-trials-refs-table th { color: var(--cb-heading); border-color: #3d4d38; }
[data-theme="dark"] .cb-trials-refs-table td { border-color: #3d4d38; color: var(--cb-text); }
[data-theme="dark"] .cb-trials-refs-table tbody tr:hover { background-color: #2d3d2a; }
[data-theme="dark"] .cb-trials-refs-table td a { color: #9bc492; }
[data-theme="dark"] .cb-trials-refs-table td a:hover { color: #c5ddc0; }
/* Team: member cards */
[data-theme="dark"] .team-card {
  background-color: #252f23;
  border-color: #3d4d38;
}
[data-theme="dark"] .team-card .card-img-wrap { background: #2d3d2a; border-color: var(--cb-green-pale); }
[data-theme="dark"] .team-card .card-body,
[data-theme="dark"] .team-card .card-title,
[data-theme="dark"] .team-card .card-text { color: var(--cb-text); }
[data-theme="dark"] .team-card .card-title { color: var(--cb-heading); }
[data-theme="dark"] .team-member-trigger,
[data-theme="dark"] .team-bio-trigger-row { color: var(--cb-green-pale); }
[data-theme="dark"] .team-member-trigger:hover,
[data-theme="dark"] .team-bio-trigger-row:hover { color: #c5ddc0; }
/* FAQ accordion */
[data-theme="dark"] .cb-accordion .accordion-item { background: #252f23; border-color: #3d4d38; }
[data-theme="dark"] .cb-accordion .accordion-button {
  background-color: #252f23 !important;
  color: var(--cb-heading) !important;
  border-bottom-color: #3d4d38;
}
[data-theme="dark"] .cb-accordion .accordion-button.collapsed { color: var(--cb-heading) !important; }
[data-theme="dark"] .cb-accordion .accordion-button:not(.collapsed) { background-color: #2d3d2a !important; color: var(--cb-green-pale) !important; border-bottom-color: #3d4d38; }
[data-theme="dark"] .cb-accordion .accordion-button:hover { background-color: #2d3d2a !important; color: var(--cb-heading); }
[data-theme="dark"] .cb-accordion .accordion-body { background-color: #252f23; color: var(--cb-text); border-top-color: #3d4d38; }
[data-theme="dark"] .cb-accordion .accordion-button::after { filter: invert(1); opacity: 0.7; }
/* Contact form */
[data-theme="dark"] .cb-contact-form-card {
  background: #252f23;
  border-color: #3d4d38;
}
[data-theme="dark"] .cb-contact-form-header { background-color: #2d3d2a; color: var(--cb-heading); }
[data-theme="dark"] .cb-contact-form-title { color: #fff; }
[data-theme="dark"] .cb-contact-form-intro,
[data-theme="dark"] .cb-contact-form-required { color: var(--cb-text); }
[data-theme="dark"] .cb-contact-form .form-label { color: var(--cb-heading); }
[data-theme="dark"] .cb-contact-form .form-control {
  background: #2d3d2a;
  border-color: #3d4d38;
  color: var(--cb-text);
}
[data-theme="dark"] .cb-contact-form .form-control::placeholder { color: #9bc492; opacity: 0.8; }
[data-theme="dark"] .cb-contact-form-footer { color: var(--cb-text); }
[data-theme="dark"] .cb-contact-form-footer a { color: #9bc492; }
[data-theme="dark"] .cb-contact-form-footer a:hover { color: #c5ddc0; }
/* Settings: show current mode in panel */
[data-theme="dark"] .cb-settings-option-active { background: rgba(155, 196, 146, 0.2) !important; color: #c5ddc0 !important; }

/* High contrast */
[data-theme="highcontrast"] {
  --cb-primary: #046bd2;
  --cb-primary-dark: #035a9e;
  --cb-green-dark: #2d4a28;
  --cb-green-pale: #3d6235;
  --cb-heading: #0d0d0d;
  --cb-text: #0d0d0d;
  --cb-bg: #ffffff;
  --cb-white: #ffffff;
  --cb-border: #0d0d0d;
  --cb-shadow: 0 2px 0 #0d0d0d;
}
[data-theme="highcontrast"] body { background-color: #fff; color: #0d0d0d; }
[data-theme="highcontrast"] a { color: #0d0d0d; text-decoration: underline; }
[data-theme="highcontrast"] a:hover { color: #2d4a28; }
[data-theme="highcontrast"] .cb-navbar-brand { text-decoration: none !important; }
[data-theme="highcontrast"] .cb-navbar-brand:hover { text-decoration: none !important; }
[data-theme="highcontrast"] nav.navbar,
[data-theme="highcontrast"] .navbar.navbar-expand-lg {
  background: #fff !important;
  border-bottom: 3px solid #0d0d0d;
}
[data-theme="highcontrast"] .navbar .navbar-nav .nav-link { color: #0d0d0d; }
[data-theme="highcontrast"] .navbar .navbar-nav .nav-link:hover { background-color: #e8f0e6; color: #2d4a28; }
[data-theme="highcontrast"] .navbar .navbar-nav .nav-link.active { color: #0d0d0d; font-weight: 700; }
[data-theme="highcontrast"] footer { background-color: #f5f5f5; border-top: 3px solid #0d0d0d; }
[data-theme="highcontrast"] .cb-settings-btn { border: 2px solid #0d0d0d; background: #fff; color: #0d0d0d; }
[data-theme="highcontrast"] .cb-settings-btn:hover { background: #e8f0e6; border-color: #2d4a28; color: #2d4a28; }
[data-theme="highcontrast"] .cb-settings-panel { border: 2px solid #0d0d0d; min-width: 14rem; padding: 0.75rem 0; }
[data-theme="highcontrast"] .cb-settings-label { font-size: 0.8rem; padding: 0.5rem 1.25rem; color: #0d0d0d; }
[data-theme="highcontrast"] .cb-settings-option { color: #0d0d0d; font-size: 1rem; padding: 0.6rem 1.25rem 0.6rem 2.5rem; }
[data-theme="highcontrast"] .cb-settings-option:hover { background: #e8f0e6; color: #2d4a28; }
[data-theme="highcontrast"] .cb-settings-option-active { font-weight: 700; background: #e8f0e6 !important; color: #0d0d0d !important; }
[data-theme="highcontrast"] .btn-primary,
[data-theme="highcontrast"] .cb-contact-submit {
  border: 2px solid #0d0d0d !important;
  background-color: #fff !important;
  color: #0d0d0d !important;
}
[data-theme="highcontrast"] .btn-primary:hover,
[data-theme="highcontrast"] .cb-contact-submit:hover {
  background-color: #e8f0e6 !important;
  color: #2d4a28 !important;
  border-color: #2d4a28 !important;
}
[data-theme="highcontrast"] .skip-link:focus { outline: 3px solid #0d0d0d; outline-offset: 2px; }
[data-theme="highcontrast"] .media-page .media-card-header { border-bottom: 2px solid #0d0d0d; }
[data-theme="highcontrast"] .media-page .media-card-header:hover { background-color: #e8f0e6; }